Go to 'thermo-' entry Go to 'dino-' entry Go to 'chondro-' entry Go to 'aero-' entry Go to '-logy' entry Go to 'thaumato-' entry Go to 'nano-' entry Go to '-sophy' entry Go to 'bucco-' entry Go to '-ism' entry Go to '-lysis' entry Go to 'galacto-' entry Go to '-anthropy' entry Go to 'pneumo-' entry Go to '-ploitation' entry Go to '-lithic' entry Go to '-sepalous' entry Go to 'onco-' entry Go to '-parous' entry Go to 'dermato-' entry Go to 'multi-' entry Go to 'dodeca-' entry Go to '-zoon' entry Go to 'vermi-' entry Go to 'crystallo-' entry Go to 'biblio-' entry Go to 'eco-' entry Go to 'juxta-' entry Go to 'facio-' entry
Affixes: the building blocks of English
Affixes: the building blocks of English

scler(o)-

Hard; hardening.

[Greek sklēros, hard.]

Sclerosis is abnormal hardening of body tissue, as in multiple sclerosis, a disease involving damage to the sheaths of nerve cells; several compound terms exist, an example being arteriosclerosis, thickening and hardening of the walls of the arteries. A scleroderma (Greek derma, skin) is a chronic hardening and contraction of the skin and connective tissue; the sclera is the hard outer layer of the eyeball; sclerotherapy is treatment of varicose blood vessels using hardening chemicals.

A scleroprotein is an insoluble structural protein such as keratin, collagen, or elastin; a sclerophyll (Greek phullon, leaf) is a woody plant with evergreen leaves that are tough and thick in order to reduce water loss; sclerenchyma (Greek enkhuma, infusion) is supporting or protective tissue composed of hardened cells, as in the skeletons of corals.

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